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Publications

Heterologous COVID-19 vaccine schedule with protein-based prime (NVX-CoV2373) and mRNA boost (BNT162b2) induces strong humoral responses: results from COV-BOOST trial.

Janani L. et al, (2025), J Infect

Plasmodium falciparum infection induces T cell tolerance that is associated with decreased disease severity upon re-infection.

Muñoz Sandoval D. et al, (2025), J Exp Med, 222

An experimental model of clinical immunity for human malaria

Hou MM. et al, (2025)

Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled, phase 2b trial in children.

Natama HM. et al, (2024), Lancet Infect Dis

Malaria: Past, Present and Future.

Salkeld J. et al, (2024), Clin Med (Lond)

Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled phase 2b trial in children

Natama HM. et al, (2024)

Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.

Wang LT. et al, (2024), Cell, 187, 4981 - 4995.e14

Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies.

King LDW. et al, (2024), Cell Rep Med, 5

Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial.

Silk SE. et al, (2024), Lancet Infect Dis

Evaluation of the precision of the Plasmodium knowlesi growth inhibition assay for Plasmodium vivax Duffy-binding protein-based malaria vaccine development.

Mertens JE. et al, (2024), Vaccine, 42, 3621 - 3629

First Phase 1b, single-center, age de-escalation trial of theP. falciparumblood-stage malaria vaccine candidate RH5.1/Matrix-M™: a delayed boost regimen induces high levels of functional antibodies in 5-17 month old Tanzanian infants

Silk SE. et al, (2024)

Evaluation of Precision of thePlasmodium knowlesiGrowth Inhibition Assay forPlasmodium vivaxDuffy-Binding Protein-based Malaria Vaccine Development

Mertens JE. et al, (2024)

PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial.

Martinez FJ. et al, (2024), NPJ Vaccines, 9

Preclinical Development of a Stabilized RH5 Virus-Like Particle Vaccine that Induces Improved Anti-Malarial Antibodies

King LDW. et al, (2024)

Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5

Wang LT. et al, (2023)

Analysis of the Diverse Antigenic Landscape of the Malaria Invasion Protein RH5 Identifies a Potent Vaccine-Induced Human Public Antibody Clonotype

Barrett JR. et al, (2023)

Reactogenicity, immunogenicity and breakthrough infections following heterologous or fractional second dose COVID-19 vaccination in adolescents (Com-COV3): A randomised controlled trial.

Kelly E. et al, (2023), J Infect, 87, 230 - 241

A systematic analysis of the human immune response to Plasmodium vivax.

Bach FA. et al, (2023), J Clin Invest

Superior antibody immunogenicity of a viral-vectored RH5 blood-stage malaria vaccine in Tanzanian infants as compared to adults.

Silk SE. et al, (2023), Med

PvDBPII-Matrix M elicits polyfunctional antibodies that limit parasite growth in a challenge trial

Martinez FJ. et al, (2023)

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