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This one-off funding call will support research teams to establish or validate correlates of protection across 11 diseases with the potential to cause substantial outbreaks or which have significant burden, and have no licenced vaccines. Having a range of reliable metrics to predict vaccine efficacy will support effective vaccine development, especially in low resource settings.

This call is divided into two strands, depending on the disease pathogens studied: Part A for bacterial/parasitic diseases or Part B for viral-related diseases.

Through Part A, Wellcome will fund research on correlates of protection to support the clinical development or licensure pathway of vaccines against the following diseases:

  • Invasive non-typhoidal salmonella, (iNTS),
  • Shigella,
  • Paratyphi A,
  • Extraintestinal pathogenic E coli (ExPec),
  • Group A strep, or
  • Schistosomiasis.

In addition to the above-mentioned diseases, Wellcome and CEPI will fund research through Part B to discover correlates of protection for diseases caused by the following viruses:

  • Ebola virus (non-Zaire forms),
  • Lassa virus,
  • Marburg virus,
  • Nipah virus
  • Rift Valley Fever virus.


Up to £5 million.


Early-career researcherEstablished researcher, Leading a research programme, Mid-career researcherPostdoctoral research.

Where your administering organisation is based: Anywhere in the world (apart from mainland China).

Apply for Seeking predictors of vaccine efficacy: identifying correlates of protection to support vaccine development