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Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract and primary cause for hysterectomy, leading to considerable morbidity and high economic burden. Here we conduct a GWAS meta-analysis in 35,474 cases and 267,505 female controls of European ancestry, identifying eight novel genome-wide significant (P 

Original publication




Journal article


Nat Commun

Publication Date





Adult, Ataxia Telangiectasia Mutated Proteins, Endometriosis, Female, Forkhead Box Protein O1, Genome-Wide Association Study, Humans, Leiomyoma, Mendelian Randomization Analysis, Menorrhagia, Middle Aged, Polymorphism, Single Nucleotide, Proportional Hazards Models, Receptor, Fibroblast Growth Factor, Type 4, Signal Transduction, Telomerase, Uterine Neoplasms, White People