Thomas Lamb
Snake Bite Coordinator
Thomas Lamb is a project coordinator for antivenom research at MOCRU and the 1st Hamish Ogston Foundation Fellow. His prior clinical experience with snake-bite envenoming in India, Bangladesh and UK has resulted in a desire to improve antivenom availability and affordability to those who need it most in a timely manner.
Snake bite in Myanmar is the leading cause of acute kidney injury requiring dialysis and is estimated to cause 1,250 death/year. The principal objective of this work is to conduct a dose-finding study of a novel lyophilized Daboia siamensis antivenom produced in Myanmar. The optimal dose will seek to reverse the effects of venom in a single dose whilst limiting the incidence of severe adverse reactions. In addition to the dose-finding trial, we plan to investigate snake-bite diagnostics including the 20-minute whole blood clotting test, perform a pharmacokinetic assessment of venom in humans and describe the Daboia siamensis envenoming sequelae.
Recent publications
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Lessons from the field: compound-specific management in acute pesticide poisoning.
Journal article
Verma VR. et al, (2024), Trans R Soc Trop Med Hyg, 118, 347 - 349
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Assessment and management of secondary bacterial infections complicating Mpox (Monkeypox) using a telemedicine service. A prospective cohort study.
Journal article
Moody S. et al, (2023), Int J STD AIDS, 34, 434 - 438
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Comment on Glatstein's case series of Echis coloratus envenoming in children.
Journal article
Lamb T. and Eddleston M., (2022), Clin Toxicol (Phila), 60, 661 - 662
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The 20-minute whole blood clotting test (20WBCT) for snakebite coagulopathy-A systematic review and meta-analysis of diagnostic test accuracy.
Journal article
Lamb T. et al, (2021), PLoS Negl Trop Dis, 15