Tom Williams
Honorary Visiting Research Fellow in Tropical Medicine
Tom is Professor of Haemoglobinopathy Research at Imperial College, London. Tom has worked in Kilifi since May 2000, where he now directs a programme of human genetic research with a focus on polymorphisms of the red blood cell.
He obtained his medical degree at Westminster Medical School in the University of London in 1985 and subsequently trained in Paediatrics and Tropical Medicine at a range of London hospitals including Westminster Children's Hospital, University College, the Hospital for Tropical Diseases and Imperial College. He obtained his PhD on the genetics of malaria resistance in children, from the University of London in 1999.
He has published extensively on the burden and clinical consequences of red cell genetic disorders and their relationship with malaria protection, questions which he studies using both laboratory-based and epidemiological approaches.
Recent publications
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Hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa (REACH): extended follow-up of a multicentre, open-label, phase 1/2 trial.
Journal article
Aygun B. et al, (2024), Lancet Haematol, 11, e425 - e435
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Nutritional supplementation in children with severe pneumonia in Uganda and Kenya (COAST-Nutrition): a phase 2 randomised controlled trial.
Journal article
Kiguli S. et al, (2024), EClinicalMedicine, 72
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Reducing transfusion utilization for children with sickle cell anemia in sub-Saharan Africa with hydroxyurea: Analysis from the phase I/II REACH trial.
Journal article
Power-Hays A. et al, (2024), Am J Hematol
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SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART)
Preprint
Maitland K. et al, (2024)
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A Phase I trial of Non-invasive Ventilation and seizure prophylaxis with levetiracetam In Children with Cerebral Malaria Trial (NOVICE-M Trial).
Journal article
Maitland K. et al, (2024), Wellcome Open Res, 9