Letter to the Editor: Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection.
Karp-Tatham E., O'Neill CR., Knight JC., Mentzer AJ., Chong AY.
Research into HLA-B*15:01 association with asymptomatic SARS-CoV-2 infection has so far yielded contradicting results. Using the UK Biobank cohort, we found a significant association between HLA-B*15:01 and asymptomatic infection. Our study adds more evidence for the complex role HLA alleles play in SARS-Cov-2 infection severity.