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In a clinical isolate of Burkholderia pseudomallei from Hainan, the association between the emergence of ceftazidime resistance and a novel PenA P174L allele was identified for the first time, providing an understanding of one mechanism by which ceftazidime resistance arises in B. pseudomallei.

Original publication

DOI

10.1016/j.drup.2024.101121

Type

Journal article

Journal

Drug Resist Updat

Publication Date

09/2024

Volume

76

Keywords

Burkholderia pseudomallei, Ceftazidime, Humans, China, Anti-Bacterial Agents, Melioidosis, Microbial Sensitivity Tests, Point Mutation, Drug Resistance, Bacterial, Bacterial Proteins, Alleles