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Spin and fragility are common in randomised controlled trials published in anaesthesia journals. Staying with the facts and addressing only the primary endpoint in the conclusion of clinical research reports might help reduce spin. Routinely reporting the fragility index, in turn, could deliver information about robustness, enhancing the transparency of positive dichotomous results. It is in the best interest of clinical research that authors, reviewers, and journals come together to reduce spin and address the fragility of randomised controlled trials.

Original publication




Journal article


Br J Anaesth

Publication Date





507 - 510


binary outcomes, fragility, randomised controlled trial, robustness, spin, trial design, Humans, Anesthesia, Anesthesiology, Anesthetists, Randomized Controlled Trials as Topic