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A 57 years female from the hills of Nepal presented with upper gastrointestinal bleeding with gastric ulcer evident on endoscopy. Though initially treated with Helicobacter pylori ( H. pylori) eradication therapy alone, biopsy later on revealed both mucormycosis and H. pylori infection. She was then treated with antifungals liposomal amphotericin B followed by posaconazole which led to complete recovery. Mucormycosis is a rare but life-threatening fungal disease of immunocompromised host though our patient was immunocompetent. If recognized and treated at early stage, as in our patient, prognosis is good. A high index of suspicion is required for considering this disease in H. pylori endemic regions such as Nepal, and is crucial for early recognition and treatment.

Original publication

DOI

10.12688/wellcomeopenres.15026.2

Type

Journal article

Journal

Wellcome Open Res

Publication Date

2019

Volume

4

Keywords

gastric mucormycosis, helicobacter pylori, mucormycosis, peptic ulcer disease, upper gastrointestinal disease