Brian D Nicholson
MRCGP BSc MSc (Health Res) DPhil
Associate Professor
- NHS General Practitioner
- NIHR Cancer Awareness Screening and Early Diagnosis Policy Research Unity - Co-Director
- CRUK Postdoctoral Fellow
- Affiliate Investigator - KPWHRI
Contact information
+44 (0)1865 289300
Diagnosis and Cancer in Primary Care
Brian's academic interests include cancer, global health, and evidence-based diagnosis.
His research aims to improve the diagnostic process for patients with symptoms of cancer. This work focusses on understanding symptoms, appropriate test use, and developing clinical pathways. He leads the departmental Cancer Theme that conducts research in four main areas: health records data; implementation science; diagnostic reasoning; and clinical trials and prospective studies. He is Early Detection lead for the CRUK Oxford Cancer Centre investigating community-based multi-cancer early detection testing.
He currently supervises 4 full time DPhil students, 2 part time EBHC students, one postdoc and one ACF. He is a GP in Oxford City.
Key publications
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A manifesto for improving cancer detection: four key considerations when implementing innovations across the interface of primary and secondary care.
Journal article
Dowrick A. et al, (2024), Lancet Oncol
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Multi-cancer early detection test in symptomatic patients referred for cancer investigation in England and Wales (SYMPLIFY): a large-scale, observational cohort study.
Journal article
Nicholson BD. et al, (2023), Lancet Oncol, 24, 733 - 743
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Evaluation of the diagnostic accuracy of two point-of-care tests for COVID-19 when used in symptomatic patients in community settings in the UK primary care COVID diagnostic accuracy platform trial (RAPTOR-C19).
Journal article
Nicholson BD. et al, (2023), PLoS One, 18
Recent publications
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Journal article
Martinez-Gutierrez J. et al, (2024), BJGP Open
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Journal article
Jackson A. et al, (2024), Lancet Oncol, 25, 1476 - 1486