STK receptor tyrosine kinase regulates susceptibility to infection with Listeria monocytogenes.
Lutz MA., Gervais F., Bernstein A., Hattel AL., Correll PH.
We have previously identified the STK receptor tyrosine kinase as a key regulator of macrophage activation and cell-mediated immune responses. Here we demonstrate that, although MSP activation of STK inhibits NO production by macrophages in response to heat-killed Listeria monocytogenes, STK-deficient mice exhibit increased susceptibility to infection with Listeria.