Andrew Carr
MA ChM DSc FRCS FMedSci
Nuffield Professor of Orthopaedics
- Former Head of Department NDORMS
- Former Director of the Botnar Institute for Musculoskeletal Sciences
- Former Director NIHR Musculoskeletal Biomedical Research Unit
Professor Andrew Carr ChM DSc FRCS FMedSci is a surgeon and clinical scientist. He was born in Bradford and studied medicine at Bristol University before training in Sheffield, Oxford, Seattle and Melbourne. He holds the Nuffield Professorship of Orthopaedics at Oxford University and is a fellow of Worcester College, Oxford.
His research over 40 years has had a significant influence on the management of patients undergoing orthopaedic surgery. Whilst working with John Goodfellow, he defined the use of the Oxford Knee as a partial knee replacement which has been implanted in over two million people worldwide. He pioneered the increased involvement of patients in assessing the effectiveness of orthopaedic surgery. The Oxford Scores he co-developed with Ray Fitzpatrick are now used globally to assess patient outcomes and direct national health policies for joint replacement operations. He has focussed on improving the interdisciplinary skills and infrastructure required for large scale surgical trials and has led and contributed to both UK and international multicentre trials. He has led the controversial use of placebo controls in surgical trials which has resulted in the decommissioning of ineffective operations. His work on chronic musculoskeletal pain has identified the importance of unresolved inflammation and, collaborating with Irene Tracey, established the importance of central pain sensitisation as a contributor to chronic musculoskeletal pain. He is one of the 25 most cited surgical researchers globally with over 250 publications, including over 40 in the Lancet, BMJ, Science Translational Medicine, Cell and Nature Biotechnology.
He was head of the Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences for 21 years during which time the department grew from 20 to over 450 research staff and DPhil students. He founded and directed the Botnar Institute of Musculoskeletal Sciences (2009-2021) and was Director of the NIHR Biomedical Research Unit (2008-2018). He was Divisional Director of the Nuffield Orthopaedic Centre specialist NHS hospital (2011-2014) during its merger to form Oxford University Hospitals NHS foundation trust. He was instrumental in the move of the Kennedy Institute to Oxford in 2011 with a benefaction of over £75million from the Kennedy Trust for Rheumatology.
He is currently Deputy Chair of the board of trustees of Bristol University, a Nuffield Medical trustee, a council member and trustee of the Royal College of Surgeons of England and an NIHR senior investigator. He has received numerous national and international awards including an honorary Doctorate from the University of Copenhagen and a fellowship of the Academy of Medical Sciences.
Key publications
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Journal article
Beard DJ. et al, (2017), The Lancet
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Serious adverse events and lifetime risk of reoperation after elective shoulder replacement: population based cohort study using hospital episode statistics for England
Journal article
CRAIG R. et al, (2019), BMJ
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The clinical and cost effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised trial
Journal article
BEARD D. et al, (2019), The Lancet
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Arthroscopic Hip Surgery compared with Physiotherapy and Activity Modification for the Treatment of Symptomatic Femoroacetabular Impingement: A Multi-Centre Randomised Controlled Trial
Journal article
PALMER ANTONY. et al, (2019), BMJ
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Journal article
Dakin SG. et al, (2015), Science Translational Medicine, 7
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Journal article
Cooper C. et al, (2016), Lancet Diabetes Endocrinol, 4, 393 - 402
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Journal article
Wartolowska K. et al, (2014), BMJ, 348, g3253 - g3253
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Journal article
Birkmeyer JD. et al, (2013), Lancet, 382, 1121 - 1129
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Journal article
Price AJ. et al, (2018), Lancet, 392, 1672 - 1682
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Journal article
Dawson J. et al, (2010), BMJ, 340
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Journal article
Mitchell C. et al, (2005), BMJ, 331, 1124 - 1128
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Medial unicompartmental arthroplasty. A survival study of the Oxford meniscal knee.
Journal article
Carr A. et al, (1993), Clin Orthop Relat Res, 205 - 213
Recent publications
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Preprint
Sander IL. et al, (2024)
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Journal article
Beard DJ. et al, (2024), Health Technol Assess, 28, 1 - 97
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Journal article
Ng MTH. et al, (2024), Nat Commun, 15
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Journal article
Ng MTH. et al, (2024), Nature Communications, 15
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Journal article
Abhari R. et al, (2023), Tissue Eng Part A