A research study led by the University of Oxford provides a transformational new insight into how antimicrobial resistance (AMR) emerges in patients with bacterial infections. The findings, published today in the journal Nature Communications, could help develop more effective interventions to prevent AMR infections developing in vulnerable patients.
Schistosomiasis is a poorly understood tropical disease that is estimated to affect over 250 million people with approximately 779 million people at risk globally. Over 90% of these individuals live in sub-Saharan Africa.
A vaccine developed by the Oxford Vaccine Group\u2019s Prof Teresa Lambe and supported in clinical trials and manufacture scale-up by researchers from the Jenner Institute (Nuffield Department of Medicine) has been recommended for inclusion in a ring vaccination trial to combat a Sudan ebolavirus outbreak in Uganda.
The Rockefeller Foundation has announced $3 million in new funding for Global.health (G.h) \u2013 a first-of-its-kind, open-source platform for scientific pandemic data. This will enable it to expand its international partnerships and modernize the global effort around coordinated pandemic prevention, surveillance, and response.
A new study, led by researchers at the University of Oxford, UK, in collaboration with the University of California, Berkeley, USA, published in The Lancet Diabetes & Endocrinology identifies, as early as the 5th month of pregnancy, patterns of fetal abdominal growth associated with maternal lipid metabolites that track newborn growth, adiposity and development into childhood.
Researchers have created a mathematical model to predict genetic resistance to antimalarial drugs in Africa to manage one of the biggest threats to global malarial control.
Congratulations to Professor Chris Lavy, who has been appointed to the World Health Organization\u2019s (WHO) technical advisory group for integrated clinical care for a period of two years.
Oxford University\u2019s Professor Teresa Lambe, the designer of the vaccine, fears Marburg disease is \u2018now being seen in places where it\u2019s never been seen before\u2019
The new air-powered hand provides a lightweight, low-maintenance and easy-to-use body-powered prosthetic option particularly well suited for children and those in low and middle-income countries.
MORU Tropical Health Network researchers in Southeast Asia study various aspects of hepatitis B and C, infections that can lead to chronic liver diseases, and complications like liver cancer or cirrhosis. Researchers at MOCRU work on treatment for hepatitis C, a frequent opportunistic infection in HIV patients. MORU\u2019s Clinical Pharmacology conducts two trials on possible treatments of hepatitis C. Hepatitis B is frequently transmitted from mother to child at birth, and SMRU researchers study mothers\u2019 knowledge and behaviour, as well as prevention.
Oxford researchers have discovered a gene that regulates pain sensitisation by amplifying pain signals within the spinal cord, helping them to understand an important mechanism underlying chronic pain in humans and providing a new treatment target.
Funding to train the next generation of cutting-edge antimicrobial resistance researchers has been announced by Ineos Oxford Institute (IOI), the University of Oxford, and the University of Cambridge.
A first-of-its kind randomised controlled trial compared two different antitoxin treatments for tetanus. A comparison of human and equine intramuscular antitoxin in adults found that intramuscular equine antitoxin is safe and effective for treating tetanus in adults. Addition of additional intrathecal (spinal) antitoxin does not add any benefit compared to treatment with intramuscular antitoxin alone.
The LEGO Foundation is awarding a \u00a311 million five-year grant to international research aimed at developing and providing free, evidence-based, playful parenting support to every parent all over the world.
During the first nine months of the COVID-19 pandemic, paediatric cancer patients from lower- and middle-income countries (LMICs) faced a higher risk of all-cause mortality than those in high-income countries, according to an international study led by the University of Oxford.
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) researchers and several international collaborators have been awarded funding from the Chan Zuckerberg Initiative to deliver an ancestrally diverse musculoskeletal atlas of healthy tissues.
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